Assessment of baseline sFLCs is recommended by IMWG guidelines 
and a European expert panel 
) to assess risk of progression.
National Comprehensive Cancer Network® (NCCN®) guidelines also recommend sFLC analysis alongside serum protein electrophoresis (SPE) and sIFE in a panel of tests for surveillance/follow-up of solitary plasmacytoma after primary treatment (Section 25.8
. Similar recommendations were recently reported by a European expert panel 
. They recommend that when measurable concentrations of a monoclonal protein or sFLCs are present, the IMWG uniform response criteria 
be used for response assessment (Section 25.3.5