28.7.4. NCCN Clinical Practice Guidelines In Oncology (NCCN Guidelines®) for Systemic Light Chain Amyloidosis V.1.2019

Chapter 28.7.4.

The guidelines developed by the National Comprehensive Cancer Network® (NCCN®) on the management of AL amyloidosis [1211] indicate that FLC analysis is necessary for hematologic response assessment and are based on international consensus guidelines, described in Section 28.7.2 [23]. The guidelines also state that renal insufficiency leads to an increase in sFLC concentrations and recommend that in such cases the κ/λ sFLC ratio or dFLC is monitored.