Serum free light chain publications
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31 |
SECTION 6 - Appendices |
| Serum free light chain publications |
Contents |
1999
- Bradwell AR, Drew R, Showell PJ, Carr-Smith HD, Mead GP. Clinical potential of free immunoglobulin light-chain measurements. Clin Chem 1999;45(6):181a
- Tang LX, Showell PJ, Mead GP, Carr-Smith HD, Drew R, Bradwell AR. An automated nephelometric immunoassay for quantification of free light-chains in human serum and urine. Clin Chem 1999;45(s6):179a
2000
- Bradwell AR, Tang LX, Drayson MT, Drew RL. Immunoassays for detection of free light chains in sera of patients with nonsecretory myeloma. Blood 2000;96(16):4906a
- Carr-Smith HD, Edwards J, Showell P, Drew R, Tang LX, Bradwell AR. Preparation of an immunoglobulin free light-chain reference material. Clin Chem 2000;46(6):699a
- Harris J, Tang LX, Showell PJ, Carr-Smith HD, Drew R, Bradwell AR. Assays for immunoglobulin free light chains in serum on the Beckman IMMAGE™. Clin Chem 2000;46(6):A180a
- Tang LX, Showell P, Carr-Smith HD, Mead GP, Drew R, Bradwell AR. Evaluation of F(ab)2-based latex enhanced nephelometric reagents for free immunoglobulin light-chains on the Behring Nephelometer II. Clin Chem 2000;46(6):705a
2001
- Abraham RS, Bergen RH, Naylor S, Katzmann JA, Bradwell AR, Kyle RA, Fonseca R. Characterisation of free immunoglobulin light chains (LC) by mass spectroscopy in light chain-associated (AL) amyloidosis. Blood 2001;98(11):3772a
- Abraham RS, Katzmann J, Clark RJ, Lymp JF, Dispenzieri A, Lust JA, Bradwell AR. Light chain myeloma: Correlation of serum nephelometric analysis for the quantitation of immunoglobulin free light chain with urine Bence Jones protein. Clin Chem 2001;47(6):108a
- Abraham RS, Katzmann JA, Clark RJ, Dispenzieri A, Lust JA, Bradwell AR, Kyle RA. Detection of serum immunoglobulin free light chains in primary amyloidosis and light chain deposition disease by nephelometry. Clin Chem 2001;47(6):107a
- Bradwell AR, Drayson MT, Mead GP. Measurement of free light chains in urine (letter - reply). Clin Chem 2001;47(11):2069-70
- Bradwell AR, Smith L, Drayson MT, Mead GP, Carr Smith HD. Serum free light chain measurements for identifying and monitoring patients with nonsecretory myeloma. Clin Chem Lab Med 2001;39:PO-F038a
- Bradwell AR, Mead GP, Carr Smith HD, Drayson MT. Detection of Bence Jones myeloma and monitoring of myeloma chemotherapy using serum immunoassays specific for free immunoglobulin light chains. Blood 2001;98:633a
- Bradwell AR, Carr-Smith HD, Mead GP, Tang LX, Showell PJ, Drayson MT, Drew R. Highly sensitive, automated immunoassay for immunoglobulin free light chains in serum and urine. Clin Chem 2001;47(4):673-80 PMID: 11274017
- Bradwell AR, Carr-Smith HD, Smith L, Mead GP. Detection and monitoring of nonsecretory myeloma using an assay for free light chains in serum. Clin Chem 2001;47(6):142a
- Carr-Smith HD, Smith L, Showell P, Mead GP, Drayson MT, Bradwell AR. Detection and monitoring of nonsecretory myeloma using assay for free light chains in serum. Hematol J 2001;1:71a
- Carr-Smith HD, Smith L, Showell P, Mead GP, Drayson MT, Bradwell AR. Development of serum free immunoassays for the detection and monitoring of patients with Bence Jones myeloma. Hematol J 2001;1:70a
- Clark RJ, Katzmann JA, Abraham RS, Lymp JF, Kyle RA, Bradwell AR. Detection of monoclonal free light chains by nephelometry: Normal ranges and relative sensitivity. Clin Chem 2001;47(6):90a
- Drayson M, Tang LX, Drew R, Mead GP, Carr-Smith H, Bradwell AR. Serum free light-chain measurements for identifying and monitoring patients with nonsecretory multiple myeloma. Blood 2001;97(9):2900-2 PMID: 11313287
- Graziani MS, Merlini G. Measurement of free light chains in urine. Clin Chem 2001;47(11):2069-70 PMID: 11673389
- Hansson LO, Dijlai-Merzog R, Danielsson O, Bradwell AR. Quantitation of the free light chain kappa and lambda serum, urine and cerebrospinal fluid (CSF) using The Binding Site F(ab)2-based nephelometric method on the IMMAGE® system. Clin Chem 2001;47(6):106a
- Katzmann JA, Clarke RJ, Abraham RS, Lymp JF, Carr-Smith HD, Kyle RA, Bradwell AR. Detection of monoclonal free light chains in serum by nephelometry: Normal ranges and relative sensitivity. Presented at Monoclonal Gammopathies and the Kidney 2001;OC1a
- Mead GP, Carr-Smith HD, Drayson MT, Hawkins PN, Bradwell AR. Serum free light chain immunoassays as an aid in the diagnosis and monitoring of light chain monoclonal gammopathies. J Bone Miner Metab 2001;19:44a
- Smith L, Mead GP, Carr-Smith HD, Drayson MT, Bradwell AR. Development of serum free light chain immunoassays for the detection and monitoring of patients with Bence Jones myeloma. Clin Chem 2001;47(6):141a
- Smith L, Mead GP, Carr-Smith HD, Drayson MT, Bradwell AR. Detection and monitoring of Bence Jones myeloma using serum free light chain measurements. Clin Chem Lab Med 2001;39:F039a
2002
- Abraham RS, Clark RJ, Bryant SC, Lymp JF, Larson T, Kyle RA, Katzmann JA. Correlation of serum immunoglobulin free light chain quantification with urinary Bence Jones protein in light chain myeloma. Clin Chem 2002;48(4):655-7 PMID: 11901068
- Abraham RS, Charlesworth MC, Owen BA, Benson LM, Katzmann JA, Reeder CB, Kyle RA. Trimolecular complexes of lambda light chain dimers in serum of a patient with multiple myeloma. Clin Chem 2002;48(10):1805-11 PMID: 12324506
- Bradwell AR, Carr-Smith HD, Mead GP, Drayson MT. Serum free light chain immunoassays and their clinical application. Clin Appl Imm Rev 2002;3:17-33
- Bradwell AR, Mead GP, Drayson MT, Carr-Smith HD. Serum immunoglobulin free light chain measurement in intact immunoglobulin myeloma. Blood 2002;100(11):5054a
- Bradwell AR, Drayson MT, Mead GP, Galvin G, Gasparetto C. Serum free light chain immunoassay for monitoring patients with light chain producing and nonsecretory myeloma. Blood 2002;100(11):5091a
- Bradwell AR, Carr-Smith H, Mead G, Harvey T. Management of patients with light chain myeloma using serum free light chain immunoassays. Clin Chem 2002;48(6):A51a
- Carr-Smith HD, Showell P, Bradwell AR. Development and evaluation of turbidimetric reagents for measuring free immunoglobulin light-chains on the Hitachi 911/912. Clin Chem Lab Med 2002;s:43a
- Carr-Smith HD, Showell PJ, Matters DJ, Long JM, Bradwell AR. Development and evaluation of nephelometric reagents for measuring free immunoglobulin light-chains on a modified Minineph™ Clin Chem Lab Med 2002;s:44a
- Carr-Smith HD, Mead GP, Drayson MT, Hawkins PN, Bradwell AR. Detection and monitoring of light chain monoclonal gammopathies using serum free light chain immunoassays. Clin Chem Lab Med 2002;s:42a
- Carr-Smith HD, Showell P, Bradwell AR. Antigen excess assessment of free light chain assays on the Dade-Behring BNII nephelometer. Clin Chem 2002;48(6):23a
- Comenzo RL, Gertz MA. Autologous stem cell transplantation for primary systemic amyloidosis. Blood 2002;99(12):4276-82 PMID: 12036853
- Hermsen D, Bradwell AR, Reinaauer H. Evaluation of an automated nephelometric immunoassay for quantification of free light chains in serum. J Lab Med 2002;26:Q18a
- Hofmann W, Guder WG, Bradwell AR, Garbrecht M. Detection of free kappa and lambda light chain in serum and urine in patients with monoclonal gammopathy. Onkologie 2002;25:752a
- Hofmann W, Guder WG, Bradwell AR, Garbrecht M. Kappa and lambda light chain in serum and urine in patients with monoclonal gammopathy. J Lab Med 2002;26:19a
- Katzmann JA, Clark RJ, Abraham RS, Bryant S, Lymp JF, Bradwell AR, Kyle RA. Serum reference intervals and diagnostic ranges for free kappa and free lambda immunoglobulin light chains: relative sensitivity for detection of monoclonal light chains. Clin Chem 2002;48(9):1437-44 PMID: 12194920
- Lachmann HJ, Gallimore R, Gillmore JD, Carr-Smith HD, Bradwell AR, Hawkins PN. Changes in the concentration of circulating free immunoglobulin chains and outcome in systemic AL Amyloidosis. Blood 2002;100(11):5090a
- Lachmann HJ, Gallimore R, Gillmore JD, Smith L, Bradwell AR, Hawkins PN. Correlation of changes in nephelometric quantification of serum monoclonal free light chains following chemotherapy and outcome in systemic AL amyloidosis. Clin Chem 2002;48:E46a
- Lachmann HJ, Gallimore R, Gillmore JD, Smith L, Bradwell AR, Hawkins PN. Detection of monoclonal free light chains by nephelometry in systemic AL amyloidosis. Clin Chem 2002;48:E45a
- Le Bricon T, Bengoufa D, Benlakehal M, Bousquet B, Erlich D. Urinary free light chain analysis by the Freelite immunoassay: a preliminary study in multiple myeloma. Clin Biochem 2002;35(7):565-7 PMID: 12493586
- Marien G, Oris E, Bradwell AR, Blanckaert N, Bossuyt X. Detection of monoclonal proteins in sera by capillary zone electrophoresis and free light chain measurements. Clin Chem 2002;48(9):1600-1 PMID: 12194945
- Marien G, Bradwell AR, Blanckaert N, Bossuyt X. Detection of monoclonal proteins in sera by capillary zone electrophoresis and free light-chain measurements. Clin Chem 2002;48(6):E52a
- Mead GP, Stubbs PD, Carr-Smith HD, Drew R, Drayson MT, Bradwell AR. Nephelometric measurement of serum free light chains in nonsecretory myeloma. Clin Chem 2002;48(s6):70a
- Mead GP, Carr-Smith HD, Drayson MT, Bradwell AR. Detection of Bence Jones myeloma and monitoring of myeloma chemotherapy using immunoassays specific for free immunoglobulin light chains. Br J Haematol 2002;117(s1):195a
- Showell PJ, Matters DJ, Long JM, Carr-Smith HD, Bradwell AR. Evaluation of latex-enhanced nephelometric reagents for measuring free immunoglobulin light-chains on a modified Minineph™. Clin Chem 2002;48(s6):A67a
- Showell PJ, Long JM, Carr-Smith HC, Bradwell AR. Evaluation of latex-enhanced turbidimetric reagents for measuring free immunoglobulin light-chains on the Hitachi 911/912. Clin Chem 2002;48(s6):A66a
- Sirohi B, Powles R, Kulkarni S, Carr-Smith HD, Sankpal S, Patel G et al. Serum free light chain assessment in myeloma patients who are in complete remission by immunofixation. Blood 2002;100(11):5095a
- Tate JR, Grimmett K, Mead GP, Cobcroft R, Gill D. Free light chain ratios in the serum of myeloma patients in complete remission following autologous peripheral blood stem cell transplantation. Clin Chem 2002;48(s6):E50a
2003
- Abraham RS, Katzmann JA, Clark RJ, Bradwell AR, Kyle RA, Gertz MA. Quantitative analysis of serum free light chains. A new marker for the diagnostic evaluation of primary systemic amyloidosis. Am J Clin Pathol 2003;119(2):274-8 PMID: 12579999
- Alyanakian MA, Abbas A, Delarue R, Arnulf B, Bradwell AR, Aucouturier P. Free immunoglobulin light chains serum levels in the follow-up of patients with monoclonal gammopathies: correlation with the 24H urinary light-chain excretion. Clin Chem 2003;49:D54a
- Arneth B, Fischer C, Birklein F, Lackner KJ. The suitability of kappa free light chains in cerebrospinal fluid diagnostics. Clin Chem Lab Med 2003;41(10):P7.85a
- Bradwell AR, Mead G, Carr-Smith H, Galvin G, Pratt G. Efficacy of high dose myeloma treatment and response to individual chemotherapy agents in myeloma is indicated by changes in serum free light chain concentrations. Blood 2003;102(11):2547a
- Bradwell AR, Carr-Smith HD, Mead GP. Clinical utility of serum free light chain assays. Clin Chem Lab Med 2003;41(Special supplement)
- Bradwell AR, Mead GP, Drayson MT, Kyle RA, Katzmann JA. Role of serum free light chain measurements in disease diagnosis and monitoring. Haematologica 2003;4(s1):P7.4a
- Bradwell AR, Carr-Smith HD, Mead GP, Harvey TC, Drayson MT. Serum test for assessment of patients with Bence Jones myeloma. Lancet 2003;361(9356):489-91 PMID: 12583950
- Bradwell AR, Galvin GP, Mead GP, Carr-Smith HD. Practical use of serial measurements of serum free light chains to monitor response to treatment of multiple myeloma. Blood 2003;102(11):5234a
- Bradwell AR. Clinical applications of serum free light chain immunoassays. Clin Lab Int 2003;November
- Carr-Smith HD, Mead GP, Smith L, Drayson MT, Bradwell AR. Serum free light chain levels in patients with intact immunoglobulin myeloma. Br J Haematol 2003;121(s1):198a
- Carr-Smith HD, Smith LJ, Bradwell AR. Serum free light chain assay development - specificity, sensitivity, standardisation and protocols. Clin Chem Lab Med 2003;41(Special supplement)
- Cohen AD, Zhou P, Xiao Q, Fleisher M, Kalakonda N, Akhurst T et al. An unusual clinicopathologic association: Systemic AL amyloidosis due to non-Hodgkin's lymphoma. Blood 2003;102(11):4838a
- Durie BG, Kyle RA, Belch A, Bensinger W, Blade J, Boccadoro M et al. Myeloma management guidelines: a consensus report from the Scientific Advisors of the International Myeloma Foundation. Hematol J 2003;4(6):379-98 PMID: 14671610
- Graziani M, Merlini G, Petrini C. Guidelines for the analysis of Bence Jones protein. Clin Chem Lab Med 2003;41(3):338-46 PMID: 12705344
- Helmke KH, Oppermann MO, Teuber WT, Michels HM, Ventur YV, Welcker MW, Landenberg PL. Freie immunglobulin-leichtketten im serum bei rheumatischen erkrankungen. Z Rheumatol 2003;62(s1):Fr40a
- Hermsen D, Bradwell AR. Nephelometric detection of free kappa and lambda light chains in serum in patients with suspected monoclonal gammopathy. Onkologie 2003;26:697a
- Herzog W, Hofmann W. Detection of free kappa and lambda light chains in serum and urine in patients with monoclonal gammopathy. Blood 2003;102(11):5190a
- Hoffman U, Opperman M, Kuchler S, Ventur Y, Teuber W, Michels H et al. Free immunoglobulin light chains in patients with rheumatic diseases. Z Rheumatol 2003;62(s1):Fr40a
- Hofmann W, Herzog W. Detection of free kappa and lambda light chain in serum and urine in patients with monoclonal gammopathy. Onkologie 2003;26:694a
- Hunter HM, Peggs K, Powles R, Apperley J, Mahendra P, Canenagh J et al. A comparison of outcome for patients undergoing non-myeloablative stem cell transplantation compared to conventional conditioning for multiple myeloma. Blood 2003;102(11):2705a
- Jaccard A, Moreau P, Aucouturier P, Ronco P, Fermand JP, Hermine O. Amylose immunoglobulinique. Hematologie 2003;9(6):485-95
- Katzmann JA, Clark RJ, Rajkumar VS, Kyle RA. Monoclonal free light chains in sera from healthy individuals: FLC MGUS. Clin Chem 2003;49:A74a
- Keren DF. Techniques to measure free kappa and free lambda light chains in serum and/or urine. Protein electrophoresis in clinical diagnosis. Arnold (Hodder Headline), 2003
- Lachmann HJ, Gallimore R, Gillmore JD, Carr-Smith HD, Bradwell AR, Pepys MB, Hawkins PN. Outcome in systemic AL amyloidosis in relation to changes in concentration of circulating free immunoglobulin light chains following chemotherapy. Br J Haematol 2003;122(1):78-84 PMID: 12823348
- Martin W, Clark RJ, Shanafelt T, Katzmann JA, Bradwell AR, Abraham R et al. Detection of serum free light chains in patients with B-cell non-Hodgkin lymphoma (NHL) and chronic lymphocytic leukemia (CLL). Blood 2003;102(11):4827a
- Mead GP, Carr-Smith H, Drayson M, Bradwell AR. Serum free light chain concentrations and their use for disease monitoring in multiple myeloma patients with intact immunoglobulin monoclonal proteins. Haematologica 2003;4(s1):170a
- Mead GP, Carr-Smith HD, Drayson MT, Bradwell AR. Serum free light chain levels in patients with intact immunoglobulin myeloma. Clin Chem 2003;49:D61a
- Mead GP, Carr-Smith HD, Drayson MT, Bradwell AR. Diagnosis and monitoring of multiple myeloma using serum free light chain concentrations. Onkologie 2003;26:695a
- Mead GP, Carr-Smith HD, Drayson MT, Bradwell AR. Elevated serum free light chain concentrations in multiple myeloma patients with intact immunoglobulin monoclonal proteins; their use for disease monitoring. Hematol J 2003;4(2):407a
- Mead GP, Carr-Smith HD, Drayson MT, Bradwell AR. Serum free light chain assays provide improved monitoring of myeloma therapy. Br J Haematol 2003;121(s1):205a
- Mead GP, Drayson MT, Carr-Smith HD, Bradwell AR. Measurement of immunoglobulin free light chains in serum. Clin Chem 2003;49(11):1957-8 PMID: 14578337
- Mead GP, Pratt G, Bradwell AR. Frequent measurement of total immunoglobulin and serum free light chains in myeloma patients during peripheral blood stem cell transplantation. Haematologica 2003;4(s1):171a
- Myers B, Lachmann H, Russell NH. Novel combination chemotherapy for primary (AL) amyloidosis myeloma: clinical, laboratory and serum amyloid-P protein scan improvement. Br J Haematol 2003;121(5):816-7 PMID: 12780799
- Myers B, Russell NH, McMillan AK. Use of a novel combination chemotherapy for AL-Amyloidosis: cyclophosphamide, thalidomide and dexamethasone - serum free light chain (SFLC) and serum amyloid protein P (SAP) scan results. Blood 2003;102(11):5249a
- Nowrousian MR, Brandhorst D, Daniels R, Sammet C, Schuett P, Ebeling P et al. Free light-chain measurement in serum compared with immunofixation of urine in patients with multiple myeloma. Blood 2003;102(11):5197a
- Nowrousian MR, Brandhorst D, Daniels R, Sammet C, Schuett P, Ebeling P, Seeber S. Comparison between free light chain measurement in serum and immunofixation of urine in patients with multiple myeloma. Onkologie 2003;26(s5):696a
- Ong S, Sethi S. Assessment of free light chain assay in serum on the Beckman Immage™. Clin Chem 2003;49(s6):D59a
- Overton J, Goodier D, Carr-Smith HD, Bradwell A. Evaluation of latex-enhanced turbidimetric reagents for measuring free immunoglobulin light-chains on the Roche Modular P. Clin Chem 2003;49(s6):D60a
- Patten PE, Ahsan G, Kazmi M, Fields PA, Chick GW, Jones RR et al. The early use of the serum free light chain assay in patients with relapsed refractory myeloma receiving treatment with thalidomide analogue (CC-4047). Blood 2003;102(11):1640a
- Rajkumar SV, Kyle RA, Therneau TM, Bradwell AR, Melton J, Katzmann JA. Presence of monoclonal free light chains in serum predicts risk of progression in monoclonal gammopathy of undetermined significance (MGUS). Blood 2003;102(11):3481a
- Showell P, Matters D, Bradwell AR. Evaluation of latex-enhanced turbidimetric reagents for measuring free immunoglobulin light-chains on the Olympus AU400. Proceedings of ACB National Meeting 2003;13a
- Showell PJ, Matters DJ, Long JM, Carr-Smith HD, Bradwell AR. Evaluation of latex-enhanced turbidimetric reagents for measuring free immunoglobulin light-chains on the Olympus AU400. Clin Chem 2003;49(s6):D55a
- Sirohi B, Powles R, Kulkarni S, Carr-Smith HD, Patel G, Das M et al. Serum free light chain assessment in myeloma patients who are in complete remission (CR) by immunofixation predicts early relapse. Blood 2003;102(s11):5195a
- Smith L, Showell P, Matters D, Carr-Smith HD, Bradwell AR. Evaluation of latex-enhanced turbidimetric reagents for measuring free immunoglobulin light-chains on the Olympus AU400. Clin Chem Lab Med 2003;41(s):W497a
- Smith LJ, Long H, Matters DJ, Carr-Smith HD, Bradwell AR. Sample storage and stability for serum free light chain assays. Clin Chem 2003;49(6):D57a
- Smith LJ, Long J, Carr-Smith HD, Bradwell AR. Measurement of immunoglobulin free light chains by automated homogeneous immunoassay in serum and plasma samples. Clin Chem 2003;49(s6):D58a
- Smith LJ, Mead GP, Bradwell AR. Comparative sensitivity of serum and urine assays for free light chains. Clin Chem Lab Med 2003;41(Special supplement)
- Smith LJ, Long J, Matters DJ, Carr-Smith HD, Bradwell AR. Sample storage and stability for free light chain assays. Proceedings of ACB National Meeting 2003;2a
- Tate JR, Gill D, Cobcroft R, Hickman PE. Practical considerations for the measurement of free light chains in serum. Clin Chem 2003;49(8):1252-7 PMID: 12881439
- Tate JR, Mollee P, Gill D. Measurement of immunoglobulin free light chains in serum: Response. Clin Chem 2003;49(11):1958
- Terpos E, Politou M, Szydio R, Nadal E, Avery S, Olavarria E et al. Autologous stem cell transplantation normalises abnormal bone resorption through the reduction of RANK/OPG ratio in multiple myeloma. Blood 2003;102(11):3658a
- Wands C, Powell M, Jupp R. The development of serum free light chain immunoassay on Bayer Advia. Proceedings of ACB National Meeting 2003;2:3a
2004
- Alyanakian MA, Abbas A, Delarue R, Arnulf B, Aucouturier P. Free immunoglobulin light-chain serum levels in the follow-up of patients with monoclonal gammopathies: correlation with 24-hr urinary light-chain excretion. Am J Hematol 2004;75(4):246-8 PMID: 15054820
- Augustson BM, Reid SD, Mead GP, Drayson MT, Child JA, Bradwell AR. Serum free light chain levels in asymptomatic myeloma. Blood 2004;104(11):4880a
- Barlogie B, Shaughnessy J, Tricot G, Jacobson J, Zangari M, Anaissie E et al. Treatment of multiple myeloma. Blood 2004;103(1):20-32 PMID: 12969978
- Berard A, Bouabdallah K. Chaines legeres libres: interet pour le diagnostic et le suivi des gammapathies monoclonales. Infos Biologiste Tribune 2004;8:12-3
- Bergen HR, Abraham RS, Johnson KL, Bradwell AR, Naylor S. Characterization of amyloidogenic immunoglobulin light chains directly from serum by on-line immunoaffinity isolation. Biomed Chromatogr 2004;18(3):191-201 PMID: 15103706
- Bird JM, Cavenagh J, Samson D, Mehta A, Hawkins P, Lachmann H. Guidelines on the diagnosis and management of AL amyloidosis. Br J Haematol 2004;125(6):681-700 PMID: 15180858
- Bouabdallah K. Interet des chaines legeres libres dans la prise en charge des patients atteints de myelome. Biologiste infos 2004;8:12-3
- Bradwell AR, Garbincius J, Holmes EW. Serum free kappa to free lambda ratios as an adjunct to serum protein electrophoresis for the detection of monoclonal proteins in the serum. Blood 2004;104(11):4856a
- Carr-Smith HD, Harland B, Anderson J, Overton J, Wieringa G, Bradwell AR. Evaluation of latex-enhanced turbidimetric reagents for measuring free immunoglobulin light chains on the Bayer Advia 1650. Clin Chem 2004;50(6):C44a
- Carr-Smith HD, Harland B, Anderson J, Overton J, Wieringa G, Bradwell AR. The effect on laboratory organisation of introducing serum free light chain assays. Clin Chem 2004;50(6):A76a
- Chou PP, Praither JD, Grainger A, Knight R. Serum free light chain assays. Clin Chem 2004;50:C24a
- Cohen AD, Zhou P, Xiao Q, Fleisher M, Kalakonda N, Akhurst T et al. Systemic AL amyloidosis due to non-Hodgkin's lymphoma: an unusual clinicopathologic association. Br J Haematol 2004;124(3):309-14 PMID: 14717777
- Cohen AD, Zhou P, Reich L, Quinn A, Fircanis S, Drake L et al. Risk-adapted intravenous melphalan followed by adjuvant dexamethazone (D) and Thalidomide (T) for newly diagnosed patients with systemic AL amyloidosis (AL): Interim results of a phase II study. Blood 2004;104(11):542a
- Dispenzieri A, Gertz MA, Kyle RA. To the editor: Determining appropriate treatment options for patients with primary systemic amyloidosis. Blood 2004;104(9):2992-3
- Engelhardt M, Rapple D, Weis A, Bisse E, Thorst G. Serum free light chain (FLC) measurement in multiple myeloma (MM) patients (pts) correlate with known monoclonal paraprotein, disease stage and therapy response. Blood 2004;104(11):4907a
- Fischer C, Arneth B, Koehler J, Lotz J, Lackner KJ. Kappa free light chains in cerebrospinal fluid as markers of intrathecal immunoglobulin synthesis. Clin Chem 2004;50(10):1809-13 PMID: 15271859
- Fischer CB, Arneth B, Koehler J, Lackner K. The suitability of kappa free light chains in cerebrospinal fluid diagnostics. Clin Chem 2004;50(6):B47a
- Gertz M, Comenzo R, Falk RH, Fermand JP, Hazenberg BP, Hawkins PN et al. Definition of organ involvement and treatment response in primary systemic amyloidosis (AL): A consensus opinion from the 10th International Symposium on amyloid and amyloidosis. Blood 2004;104(11):754a
- Gertz MA, Lacy MQ, Dispenzieri A. Therapy for immunoglobulin light chain amyloidosis: the new and the old. Blood Rev 2004;18(1):17-37 PMID: 14684147
- Gertz MA. Freelite immunoglobulin free light chain assay diagnostic: Serum test enables identification and monitoring of MM. Myeloma Today 2004;6(2):5-6
- Gertz MA, Merlini G, Treon SP. Amyloidosis and Waldenstrom's macroglobulinemia. Hematology Am Soc Hematol Educ Program 2004;257-82 PMID: 15561687
- Goodman HJB, Lachmann HJ, Bradwell AR, Hawkins PN. Intermediate dose intravenous melphalan and dexamethasone treatment in 144 patients with systemic AL amyloidosis. Blood 2004;104(11):755a
- Grateau G, Kyle RA, Skinner M. Amyloid and amyloidosis. CRC Press, 2004
- Guis L, Diemert MC, Ghillani P, Choquet S, Leblond V, Vernant JP, Musset L. The quantitation of serum free light chains: Three case reports. Clin Chem 2004;50(6):F38a
- Hermsen D, Herzog W. Nephelometric detection of serum free kappa and lambda light chains in patients with suspected monoclonal free light chain gammopathies. Clin Chem 2004;50(6):C19a
- Herzum I, Heinz R, Bruder-Burzlaff B, Renz H, Wahl HG. Reliability of the new Freelite assay for quantification of free light chains in urine. Clin Chem 2004;50(6):C36a
- Hofmann W, Garbrecht M, Bradwell AR, Guder WG. A new concept for detection of Bence Jones proteinuria in patients with monoclonal gammopathy. Clin Lab 2004;50(3-4):181-5 PMID: 15074473
- Katzmann JA, Dispenzieri A, Abraham R, Kyle R. Performance of free light chain assays in clinical practice. Blood 2004;104(11):757a
- Kyle RA, Rajkumar SV. Multiple myeloma. N Engl J Med 2004;351(18):1860-73 PMID: 15509819
- Mead GP, Reid SD, Augustson BM, Drayson MT, Bradwell AR, Child JA. Correlation of serum free light chains and bone marrow plasma cell infiltration in multiple myeloma. Blood 2004;104(11):4865a
- Mead GP, Carr-Smith HD, Drayson MT, Morgan GJ, Child JA, Bradwell AR. Serum free light chains for monitoring multiple myeloma. Br J Haematol 2004;126(3):348-54 PMID: 15257706
- Mead GP, Carr-Smith HD, Galvin G, Pratt G, Bradwell AR. Efficacy of high dose treatment and response to individual chemotherapy agents in myeloma is indicated by changes in serum free light chain concentrations. Clin Chem 2004;50(6):C20a
- Mead GP, Bradwell AR, Lovell R, Pratt G. Changes in serum free light chain concentrations after high-dose melphalan and autologous stem cell transplant in myeloma patients. Bone Marrow Transplant 2004;33(s1):380a
- Merlini G, Palladini G, Bosoni T, Lavatelli F, Melzi d'Eril G, Bradwell AR, Moratti R. Circulating free light chain concentration correlates with degree of cardiac dysfunction in AL amyloidosis. Clin Chem 2004;50(s6):B113a
- Merlini G. Editorial: Sharpening therapeutic strategy in AL amyloidosis. Blood 2004;104(6):1593-4
- Nakano T, Nagata A, Takahashi H. Ratio of urinary free immunoglobulin light chain kappa to lambda in the diagnosis of Bence Jones proteinuria. Clin Chem Lab Med 2004;42(4):429-34 PMID: 15147154
- Palladini G, Perlini S, Vezzoli M, Perfetti V, Lavatelli F, Ferrero I et al. The reduction of the serum concentration of the amyloidogenic light-chain in cardiac AL results in prompt improvement of myocardial function and prolonged survival despite unaltered amount of myocardial amyloid deposits. In: Grateau G, Kyle RA, Skinner M, eds. Amyloid and Amyloidosis. CRC Press, 2004:73-5
- Pratt G, Mead G, Lovell R, Bradwell AR. Changes in serum-free light chain concentrations as a marker of disease response in myeloma patients after autologous stem cell transplantation. Br J Haematol 2004;125(s1):94a
- Rajkumar SV, Kyle RA, Therneau TM, Melton LJI, Bradwell AR, Clark RJ et al. Presence of an abnormal serum free light ratio is an independent risk factor for progression in monoclonal gammopathy of undetermined significance (MGUS). Blood 2004;104(11):3647a
- Rajkumar SV, Kyle RA, Therneau TM, Clark RJ, Bradwell AR, Melton LJ, III et al. Presence of monoclonal free light chains in the serum predicts risk of progression in monoclonal gammopathy of undetermined significance. Br J Haematol 2004;127(3):308-10 PMID: 15491291
- Räpple D, Weis A, Deschler B, Bisse E, Ihorst G, Englehardt M. Lambda (λ)- and kappa (κ)- free light chains in multiple myeloma (MM) patients correlate with known monoclonal paraprotein, disease stage and therapy response. Onkologie 2004;27(s3):771a
- Reid SD, Mead GP, Drayson MT, Bradwell AR. Comparison of immunofixation electrophoresis with serum free light chain measurement for determining complete remission in light chain multiple myeloma. Bone Marrow Transplant 2004;33(s1):632a
- Reid SD, Drayson MT, Mead GP, Augustson B, Bradwell AR. Serum free light chains are a more sensitive marker of serological remission in multiple myeloma patients. Clin Chem 2004;50(s6):C34a
- Sanchorawala V, Wright DG, Magnani B, Skinner M, Seldin DC. Serum free light chain responses after high-dose intravenous melphalan and autologous stem cell transplantation for AL (primary) Amyloidosis. Blood 2004;104(11):942a
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2005
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- Augustson BM, Reid SD, Mead GP, Drayson MT, Child JA, Bradwell AR. Serum free light chain levels in asymptomatic myeloma. Haematologica 2005;90(s1):PO1303a
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2006
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2007
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2008
- Allen S, Vickrey E, Mehta J, Singhal S. The relationship between serum free light chain levels and serum immunofixation electrophoresis: Implications for the definition of "Stringent CR" in myeloma. Blood 2008;112(11):2724a
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- Pratt G, Mead G, Basu S, Jacobs A, Holder R, Fegan C et al. Abnormal serum free light chain ratios are associated with earlier time to first treatment and poor survival in patients with chronic lymphocytic leukaemia. Blood 2008;112(11):3141a
- Pratt G, Holding S. More studies are needed to assess the performance of serum free light chain measurement for the diagnosis of B-cell disorders in routine clinical practice - response to Vermeersch et al. Br J Haematol 2008;143(1):145-6 PMID: 18671705
- Presslauer S, Milosavljevic D, Brucke T, Bayer P, Hubl W. Elevated levels of kappa free light chains in CSF support the diagnosis of multiple sclerosis. J Neurol 2008;255(10):1508-14 PMID: 18685917
- Recasens V, Rubio-Escuin R, Rubio-Martinez A, Pascual T, Lopez N, Sanjuan M, Giraldo P. Serum free light chains profile as early biomarker with predictive value after autologous transplant in multiple myeloma. Blood 2008;112(11):5142a
- Recasens V, Rubio-Escuin R, Rubio-Martinez A, Rodriguez T, Lopez N, Giraldo P. Early predictive value of serum free light chains profile in relapsed of multiple myeloma after autologous transplant. Hematology meeting reports 2008;2(2):D33a
- Robin H, Gaertner R, Parton A, Zetlmeisl M, Garcia A, Kuus-Reichel K. Utility of serum free light chain analysis in the diagnosis of monoclonal gammopathies in a community hospital. Hematology meeting reports 2008;2(2):C17a
- Rodriguez GP, Jimenez JJ, Rodriguez MJR, de Carvalho NB, Manzanal RM, de Larramendi CH, Godoy PS. Patient with multiple myeloma, in extramedullary relapse associated to light chain excretion and disappearing of intact immunoglobulin 'light chain escape'. Hematology meeting reports 2008;2(2):D29a
- Roussou M, Kastritis E, Migkou M, Psimenou E, Grapsa I, Matsouka C et al. Treatment of patients with multiple myeloma complicated by renal failure with bortezomib-based regimens. Leuk Lymphoma 2008;49(5):890-5 PMID: 18464107
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- Schonland SO, Hansmann J, Mechtersheimer G, Goldschmidt H, Ho AD, Hegenbart U. Bone involvement in patients with systemic AL amyloidosis mimics lytic myeloma bone disease. Haematologica 2008;93(6):955-6 PMID: 18515883
- Seldin DC, Ward JE. Serum free light chain analysis, 4th Edition. Amyloid 2008;15(2):142-3 PMID: 18484342
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- Sharp K, Emond JP, Giroux M, Steiner A, Russ G, Harding S. Serum free light chain measurements by electrophoretic and nephelometric methods may differ due to the presence of aggregated light chains. Hematology meeting reports 2008;2(2):B11a
- Sheldon J. Free light chains: author's response. Ann Clin Biochem 2008;45(Pt 4):445-6 PMID: 18583639
- Showell PJ, Lynch EA, Mitchell F, Mead GP, Bradwell AR. Comparison of serum free immunoglobulin light-chain assays on eight Nephelometric/Turbidimetric analysers. Clin Chem 2008;54(s6):C92a
- Showell PJ, Lynch EA, Mitchell F. Comparison of serum free immunoglobulin light chain assays on eight nephelometric/ turbidimetric analysers. Hematology meeting reports 2008;2(2):A4a
- Showell PJ, Lynch EA, Johnson-Brett B. Evaluation of latex-enhanced turbidimetric reagents for measuring free immunoglobulin light chains on the Roche COBAS C501. Hematology meeting reports 2008;2(2):A2a
- Showell PJ, Lynch EA, Johnson-Brett B. Evaluation of latex-enhanced turbidimetric reagents for measuring free immunoglobulin light-chains on the Roche COBAS INTEGRA 800. Hematology meeting reports 2008;2(2):A3a
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- Sobas M, Perez L, de Carvalho N, Encinas MP. Serum immunoglobulin free light chains for monitoring patients with oligosecretory myeloma. Hematology meeting reports 2008;2(2):D30a
- Šcudla V, Schneiderka P, Pika T, Minarík J, Bacovsky J, Farbiaková V. Clinical importance of evaluating serum levels of free light chains of immunoglobulins in monoclonal gammopathies. Klin Biochem Metab 2008;16(37):76-83
- Špicka I, Mecl J, Benáková H, Nohejlová A, Straub J, Novotová E, Zima T. Comparing the detection of monoclonal protein by means of presently available biochemical methods. Klin Biochem Metab 2008;16(37):89-92
- Tang G, Snyder M, Rao LV. Assessment of serum free light chain (FLC) assays with immunofixation electrophoresis (IFE) and bone marrow (BM) immunophenotyping in the diagnosis of plasma cell disorders. Clin Chem 2008;54(s6):A96a
- Tate J, Bazeley S, Sykes S, Mollee P. Serum free light chain assay for diagnosis and monitoring of monoclonal light-chain diseases: analytical and clinical correlations. Ann Clin Biochem 2008;45(s1):Th40a
- Tate JR, Bazeley S, Sykes S, Mollee P. Serum free light chain assay for diagnosis and monitoring of monoclonal light-chain diseases - analytical and clinical correlations. Clin Chem 2008;54(s6):C75a
- Thio M, Blokhuis BR, Nijkamp FP, Redegeld FA. Free immunoglobulin light chains: a novel target in the therapy of inflammatory diseases. Trends Pharmacol Sci 2008;29(4):170-4 PMID: 18353446
- Tichý M, Vávrová J, Friedecký B, Maisnar V. Methods for detection of free immunoglobulin light chains. Klin Biochem Metab 2008;16(37):93-6
- Trieu Y, Xu W, Anglin P, Chen C, Kukreti V, Trudel S, Reece DE. Evaluation of serum free light chains and outcome in multiple myeloma patients with an intact monoclonal immunoglobulin treated with autologous stem cell transplantation. Blood 2008;112(11):3323a
- van Gameren II, Bijzet J, Limburg PC, Vellenga E, van Rijswijk MH, Hazenberg BP. Diagnostic performance of measuring free light chains in fat tissue of patients with AL amyloidosis. Presented at ACR Annual Scientific Meeting 2008;831a
- van Hoeven KH, Wells J, Abadie A. Serum protein electrophoresis (SPEP) and serum free light chain assays: A more sensitive approach than SPEP and urine protein electrophoresis (UPEP) for the diagnosis of monoclonal gammopathy. J Am Soc Nephrol 2008;19:SA-PO2501a
- van Hoeven KH, McBride L, Lendvai N, Gonsky J, Berges T, Siegel DS. Serum free light chain testing is a more sensitive baseline marker than urine protein electrophoresis among patients undergoing primary autologous stem cell transplantation in multiple myeloma. Hematology meeting reports 2008;2(2):B9a
- van Rhee F, Crowley J, Barlogie B. Response: Top tertile SFLC reduction indeed is an independent feature of myeloma aggressiveness. Blood 2008;111(4):2491a
- Vavrova J, Friedecky B, Tichy M, Holeckova M, Maisnar V, Hajek R. The evaluation of light chains using ELISA method. Blood 2008;112(11):5147a
- Vávrová J, Friedecký B, Tichý M, Holecková M, Maisnar V, Hájek R. The determination of free light chains by immunoturbidimetry and ELISA. Klin Biochem Metab 2008;16(37):97-101
- Vermeersch P, Marien G, Bossuyt X. More studies are needed to assess the performance of serum free light chain measurement for the diagnosis of B-cell disorders in routine clinical practice. Br J Haematol 2008;143(1):143-5 PMID: 18671704
- Vermeersch P, Van Hoovels L, Delforge M, Marien G, Bossuyt X. Diagnostic performance of serum free light chain measurement in patients suspected of a monoclonal B-cell disorder. Br J Haematol 2008;143(4):496-502 PMID: 18729849
- Vescio R. Advances in the diagnosis of multiple myeloma. Clin Adv Hematol Oncol 2008;6(4):299-300 PMID: 18496497
- Vickrey E. Multiple myeloma: vague symptoms can challenge diagnostic skills. JAAPA 2008;21(11):19-22 PMID: 19105542
- Vickrey E, Allen S, Krishnamurthy J, Singh V, Mehta J, Singhal S. The utility of serum free light chain measurement in myeloma patients with oligoclonal bands on serum or urine Immunofixation. Blood 2008;112(11):5121a
- Wechalekar AD, Lachmann HJ, Goodman HJ, Bradwell A, Hawkins PN, Gillmore JD. AL amyloidosis associated with IgM paraproteinemia: clinical profile and treatment outcome. Blood 2008;112(10):4009-16 PMID: 18708629
- Wechalekar AD, Hawkins PN, Gillmore JD. Perspectives in treatment of AL amyloidosis. Br J Haematol 2008;140(4):365-77 PMID: 18162121
- Wechalekar AD, Lachmann HJ, Offer M, Hawkins PN, Gillmore JD. Efficacy of bortezomib in systemic AL amyloidosis with relapsed/refractory clonal disease. Haematologica 2008;93(2):295-8 PMID: 18245653
- Wells JM, van Hoeven KH, Abadie JM. Serum free light chains assays in clinical practice: Impact of impaired renal function on interpretation. Clin Chem 2008;54(s6):C91a
- Went R, Chan-Lam D, Thornhill M. Isolated tongue amyloid in a patient with multiple myeloma. Br J Haematol 2008;143(5):606 PMID: 18710391
- White DA, Rose S, Galsinh S, Perry A, Parker A, Smith A. Comparison of normal and multiple myeloma samples measured by an ELISA free light chain assay (Biovendor) and the Binding Site Ltd nephelometric Freelite assay. Hematology meeting reports 2008;2(2):B15a
- Willenbacher E, Gastl G, Nachbaur D, Willenbacher W. Free light chain analysis: Is it useful to monitor patients undergoing haematological stem cell therapy for multiple myeloma? An analysis of "real life" data. Bone Marrow Transplant 2008;41(s1):674a
- Willenbacher E, Gastl G, Nachbaur D, Clausen J, Willenbacher W. Free light chain analysis: Is it useful to monitor patients undergoing hematological stem cell therapy for multiple myeloma? An analysis of 'real life' data. Hematology meeting reports 2008;2(2):D27a
- Wood P, McElroy Y, Stone MJ. Comparison of serum immunofixation electrophoresis and free light chain assays in detection of monoclonal gammopathies. Hematology meeting reports 2008;2(2):B10a
- Wurster U. Cerebrospinal fluid analysis in multiple sclerosis and neuroborreliosis: free light chains compared with oligoclonal bands and IgG, IgA, IgM synthesis. Ann Clin Biochem 2008;45(s1):T9a
2009
- Abadie JM, van Hoeven KH, Wells JM. Are renal reference intervals required when screening for plasma cell disorders with serum free light chains and serum protein electrophoresis? Am J Clin Pathol 2009;131(2):166-71 PMID:19141376
- Aggarwal R, Sequeira W, Mikolaitis R, Kokebie R, Block JA, Jolly M. Measurement of serum free light chains performs better than known immunological biomarkers for systemic lupus erythematosus disease activity. Presented at ACR/AHRP Annual Scientific Meeting 2009;916a
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- Almeshhedani M, Salamat A, Al-Ismail S. Evaluating the potential use of risk categorisation in the management of MGUS. Haematologica 2009;94(s2):969a
- Arneth B. Author's Response to Professor Reiber's second letter concerning our article: High sensitivity of free lambda and free kappa light chains for the detection of intrathecal immunoglobulin synthesis in cerebrospinal fluid. Acta Neurol Scand 2009;120(6):447-9
- Arneth B, Birklein F. High sensitivity of free lambda and free kappa light chains for detection of intrathecal immunoglobulin synthesis in cerebrospinal fluid. Acta Neurol Scand 2009;119(1):39-44 PMID:18573131
- Arrobas Velilla T, Bermudo Guitarte C, Duro Millan R, Santos Rey K, Sanchez Margalet V, Arjona Rueda I, Goberna Ortiz R. Use of serum free light chain concentrations as an early response marker in multiple myeloma (MM). Clin Chem 2009;55(s6):C69a
- Asenova S, Bacher U, Gerritzen A, Zander AR, Kröger N. Role of free light chain assay ratio to distinguish between CR according EBMT criteria or stringent complete remission (sCR) according IMWG in multiple myeloma patients. Blood 2009;114(22):1787a
- Audard V, Matignon M, Weiss L, Remy P, Pardon A, Haioun C et al. Successful long-term outcome of the first combined heart and kidney transplant in a patient with systemic AL amyloidosis. Am J Transplant 2009;9(1):236-40 PMID:19067666
- Avet-Loiseau H, Harousseau JL, Moreau P, Mathiot C, Facon T, Attal M et al. Heavy/light chain specific immunoglobulin ratios at presentation are prognostic for progression free survival in the IFM 2005-01 myeloma trial. Blood 2009;114(22):1818a
- Bakker AJ, Bierma-Ram A, Elderman-van der Werf C, Strijdhaftig ML, van Zanden JJ. Screening for M-proteinemia: serum protein electrophoresis and free light chains compared. Clin Chem Lab Med 2009;47(12):1507-11 PMID:19842994
- Bakker AJ, Bierma-Ram A, Elderman-van der Werf C, Strijdhaftig ML, van Zanden JJ. Quantitation of serum free light chains. Clin Chem 2009;55(8):1585-7 PMID:19498053
- Basnayake K, Ghonemy T, Hutchison C, Bradwell AR, Cockwell P. Immunoglobulin free light chains in situ in patients with chronic kidney disease. Presented at NKF Spring Clinical Meeting 2009
- Basnayake K, Cheung CK, Hutchison C, Cook M, Rylance P, Stoves J et al. Differential evolution of renal scarring in cast nephropathy despite early reductions in serum free light chains. Presented at NKF Spring Clinical Meeting 2009
- Bird J, Behrens J, Westin J, Turesson I, Drayson M, Beetham R et al. UK Myeloma Forum (UKMF) and Nordic Myeloma Study Group (NMSG): guidelines for the investigation of newly detected M-proteins and the management of monoclonal gammopathy of undetermined significance (MGUS). Br J Haematol 2009;147(1):22-42 PMID:19673884
- Bladé J, Rosinol L, Cibeira MT. Are all myelomas preceded by MGUS? Blood 2009;113(22):5370 PMID:19478048
- Böer K, Deufel T. Quantitation of serum free light chains does not compensate for serum immunofixation only when screening for monoclonal gammopathies. Clin Chem Lab Med 2009;47(9):1109-15 PMID:19728853
- Bradwell AR, Harding SJ, Fourrier NJ, Wallis GL, Drayson MT, Carr-Smith HD, Mead GP. Assessment of monoclonal gammopathies by nephelometric measurement of individual immunoglobulin kappa/lambda ratios. Clin Chem 2009;55(9):1646-55 PMID:19617289
- Bryce AH, Ketterling RP, Gertz MA, Lacy M, Knudson RA, Zeldenrust S et al. Translocation t(11;14) and survival of patients with light chain (AL) amyloidosis. Haematologica 2009;94(3):380-6 PMID:19211640
- Chanan-Khan AA, Jagannath S, Heffner LT, Avigan D, Lee KP, Lutz RJ et al. Phase I study of BT062 given as repeated single dose once every 3 weeks in patients with relapsed or relapsed/refractory multiple myeloma. Blood 2009;114(22):1862a
- Chee CE, Kumar S, Larson DR, Kyle RA, Dispenzieri A, Gertz MA et al. The importance of bone marrow examination in determining complete response to therapy in patients with multiple myeloma. Blood 2009;114(13):2617-8 PMID:19641191
- Cohen G, Horl WH. Free immunoglobulin light chains as a risk factor in renal and extrarenal complications. Semin Dial 2009;22(4):369-72 PMID:9708983
- Comenzo RL. How I treat amyloidosis. Blood 2009;114(15):3147-57 PMID:19617578
- Cook M, Hutchison C, Basu S, Cockwell P, Bradwell AR. FLC removal HD improves outcome in myeloma kidney. Clin Lymphoma Myeloma 2009;9(s1):A069a
- de Cruz M, Pawarova B, Lachmann H, Gillmore J, Gibbs S, Sattianayagam P et al. Early detection of cardiac systolic functional impairment and correlation with NT-ProBNP change in AL amyloidosis by cardiac lateral wall tissue Doppler S wave. Blood 2009;114(22):2814a
- De Filippi R, Iaccarino G, Frigeri F, Di FR, Crisci S, Capobianco G et al. Elevation of clonal serum free light chains in patients with HIV-negative primary effusion lymphoma (PEL) and PEL-like lymphoma. Br J Haematol 2009;147(3):405-8 PMID:19681885
- De Filippi R, Laccarino G, Frigeri F, Russo F, Di Francia R, Distinyo M et al. Serum free-immunoglobulin light chains testing is frequently abnormal in patients with B-cell Non-Hodgkin and Hodgkin Lymphoma and may change in value for prognosis and therapeutic monitoring. Clin Lymphoma Myeloma 2009;9(s1):A412a
- De Filippi R, Russo F, Iaccarino G, Crisci S, Frigeri F, Riemma C et al. Abnormally elevated levels of serum free-immunoglobulin light chains are frequently found in classic Hodgkin Lymphoma (cHL) and predict outcome of patients with early stage disease. Blood 2009;114(22):267a
- de Larrea CF, Cibeira MT, Elena M, Arostegui JJ, Rosinol L, Rovira M et al. Abnormal serum free light chain ratio in patients with multiple myeloma in complete remission has strong association with the presence of oligoclonal bands: implications for stringent complete remission definition. Blood 2009;114(24):4954-6 PMID:19797521
- Decaux O, Briand PY, Guenet L, Sebillot M, Jego P, Grosbois B. Frequency of abnormal serum free light chain ratio in a French cohort of patients with MGUS. Clin Lymphoma Myeloma 2009;9(s1):B373a
- Decaux O, Karras A. Update in multiple myeloma: international response criteria and renal complications. Rev Med Interne 2009;30(12):1080-3 PMID:19833418
- Decaux O. 5th International Symposium on clinical applications of serum free light chain analysis. Rev Med Interne 2009;30(1):96-100 PMID:19054596
- Delbes S, Bridoux F, Tennent G, Valleix S, Touchard G, Goujon JM. Predominant renal hereditary amyloidosis caused by a novel apolipoprotein (Apo) A1 variant. Presented at World Congress of Nephrology 2009;Su046a
- Diamantidis MD, Loannidou-Papagiannaki E, Ntaios G. Novel extended reference range for serum kappa/lambda free light chain ratio in diagnosing monoclonal gammopathies in renal insufficient patients. Clin Biochem 2009;42(10-11):1202-3 PMID:19375413
- Dimopoulos MA, Roussou M, Gavriatopoulou M, Zagouri F, Migkou M, Matsouka C et al. Reversibility of renal impairment in patients with multiple myeloma treated with bortezomib-based regimens: identification of predictive factors. Clin Lymphoma Myeloma 2009;9(4):302-6 PMID:19717380
- Dispenzieri A, Kyle R, Merlini G, Miguel JS, Ludwig H, Hajek R et al. International Myeloma Working Group guidelines for serum-free light chain analysis in multiple myeloma and related disorders. Leukemia 2009;23(2):215-24 PMID:19020545
- Doyle A, Soutar R, Geddes CC. Multiple myeloma in chronic kidney disease. Utility of discretionary screening using serum electrophoresis. Nephron Clin Pract 2009;111(1):c7-11 PMID:19033691
- Drayson M, Cobbold M, Goodall M, Wang Y, Birtwhistle J, Jefferis R. Monoclonal antibodies that provide a reliable new assay for serum immunoglobulin FLC in myeloma. Clin Lymphoma Myeloma 2009;9(s1):A355a
- Drayson MT, Behrens J, Cohen DR, Iggo N, Gregory WM, Bell SE et al. Serum FLC levels can be reduced rapidly; lower levels are associated with renal recovery. Clin Lymphoma Myeloma 2009;9(s1):A351a
- Drayson MT, Morgan GJ, Jackson GH, Davies FE, Owen RG, Ross FM et al. Prospective study of serum FLC and other M-protein assays: when and how to measure response? Clin Lymphoma Myeloma 2009;9(s1):A346a
- Eom HS, Min CK, Cho BS, Lee S, Lee JW, Min WS et al. Retrospective comparison of bortezomib-containing regimens with vincristine-doxorubicin-dexamethasone (VAD) as induction treatment prior to autologous stem cell transplantation for multiple myeloma. Jpn J Clin Oncol 2009;39(7):449-55 PMID:19487425
- Esperanza E, Sanchez-Navarro MR, Caffarena C, Mora-Vallellano J, Zafra-Ceres M, Samaniego-Sanchez C. Algorithm for monoclonal gammopathies diagnosis. To prospective study of incidence from our population. Haematologica 2009;94(s2):1611a
- Fernández de Larrea C, Cibeira MT, Elena M, Rosiñol L, Rovira M, Arostegui JJ et al. Abnormal serum free-light chain ratio in patients with multiple myeloma in long-lasting complete remission: strong association with oligoclonal bands. Haematologica 2009;94(s2):375a
- Fulton RB, Fernando SL. Serum free light chain assay reduces the need for serum and urine immunofixation electrophoresis in the evaluation of monoclonal gammopathy. Ann Clin Biochem 2009;46(Pt 5):407-12 PMID:19641008
- Gay F, Hayman SR, Lacy MQ, Buadi F, Gertz MA, Kumar S et al. Lenalidomide plus dexamethasone versus thalidomide plus dexamethasone in newly diagnosed multiple myeloma: a comparative analysis of 411 patients. Blood 2009;115(7):1343-50 PMID:20008302
- Giarin MM, Giaccone L, Sorasio R, Sfiligoi C, Amoroso B, Cavallo F et al. Serum free light chain ratio, total kappa/lambda ratio, and immunofixation results are not prognostic factors after stem cell transplantation for newly diagnosed multiple myeloma. Clin Chem 2009;55(8):1510-6 PMID:19520760
- Gibbs SDJ, Gillmore JD, Sattianayagam PT, Offer M, Lachmann HJ, Hawkins PN, Wechalekar AD. In AL amyloidosis, both oral melphalan and dexamethasone (Mel-Dex) and risk-adapted cyclophosphamide, thalidomide and dexamethasone (CTD) have similar efficacy as upfront treatment. Blood 2009;114(22):745a
- Gibbs SDJ, de Cruz M, Sattianayagam PT, Lachmann HJ, Gillmore JD, Hawkins PN, Wechalekar AD. Transient post chemotherapy rise in NT Pro-BNP in AL amyloidosis: implications for organ response assessment. Blood 2009;114(22):1791a
- Gibbs SDJ, Sattianayagam PT, Gillmore JD, Offer M, Lachmann HJ, Hawkins PN, Wechalekar AD. Is there a role for thalidomide maintenance in the treatment of AL amyloidosis? Blood 2009;114(22):1863a
- Gillmore J, Cocks K, Gibbs SDJ, Sattianayagam PT, Lane T, Lachmann H et al. Cyclophosphamide, thalidomide and dexamethasone (CTD) versus melphalan plus dexamethasone (MD) for newly-diagnosed systemic AL amyloidosis - results from the UK amyloidosis treatment trial. Blood 2009;114(22):2869a
- Giraldo P, Recasens V, Rubio-Escuin R, Rubio-Martinez A, Pascual T, Giraldo P. Predictive value of serum free light chains ratio in relapsed of multiple myeloma after autologous transplant. Haematologica 2009;94(s2):1615a
- Girnius S, Tsai F, Seldin DC, Quillen K, Yanarella L, Finn KT et al. Early serum free light chain responses following high-dose melphalan and stem cell transplantation for AL amyloidosis. Blood 2009;114(22):4352a
- Go RS, Doyle LM. A monoclonal gammopathy in search of clinical significance: 57 years later. Blood 2009;114(11):2355-6 PMID:19745077
- Gottenberg JE, Miceli-Richard C, Ducot B, Goupille P, Combe B, Mariette X. Markers of B-lymphocyte activation are elevated in patients with early rheumatoid arthritis and correlated with disease activity in the ESPOIR cohort. Arthritis Res Ther 2009;11(4):R114 PMID:19627580
- Groot Kormelink T, Thio M, Blokhuis BR, Nijkamp FP, Redegeld FA. Atopic and non-atopic allergic disorders: current insights into the possible involvement of free immunoglobulin light chains. Clin Exp Allergy 2009;39(1):33-42 PMID:19040467
- Harding S, Koulieris E, Kyrtsonis MC, Bradley C, Drayson M, Morgan G et al. Serum free light chain and serum heavy/ light chain ratios are independently prognostic in multiple myeloma patients. Blood 2009;114(22):4880a
- Harding S, Sharp K, Fourrier N, Margetts C, Mead G, Bradwell AR. Nephelometric immunoassays for IgGκ and IgGλ for the assessment of multiple myeloma patients. Clin Chem 2009;55(S6):C23a
- Harding SJ, Margetts C, Fourrier NJ, Drayson MT, Mead GP, Bradwell AR. Comparison of serum protein immunofixation electrophoresis, serum free light chains and heavy/light chain ratios for monitoring IgA multiple myeloma patients. Haematologica 2009;94(s2):1578a
- Harding SJ, Sharp K, Steiner A, Russ G, Blackmore S, Mead G et al. Quantification of polymerising serum free light chains. Clin Lymphoma Myeloma 2009;9(s1):B101a.
- Harding SJ, Mead GP, Hobbs JAR, Drayson MT, Bradwell AR. Free light and heavy/light chain monitoring in IgGλ sera. Clin Lymphoma Myeloma 2009;9(s2):B225a
- Harding SJ, Mead GP, Bradwell AR, Berard AM. Serum free light chain immunoassay as an adjunct to serum protein electrophoresis and immunofixation electrophoresis in the detection of multiple myeloma and other B-cell malignancies. Clin Chem Lab Med 2009;47(3):302-4 PMID:19676141
- Harding SJ, Drayson MT, Mead GP, Bradwell AR. Prognostic value of free and heavy/light chain analysis. Clin Lymphoma Myeloma 2009;9(s2):B555a
- Harding SJ, Alvi A, Margetts C, Plant T, Drayson M, Mead G, Bradwell AR. Immunoglobulin ratios: an alternative to immunofixation. Clin Lymphoma Myeloma 2009;9(s2):B596a
- Harousseau JL, Attal M, Avet-Loiseau H. The role of complete response in multiple myeloma. Blood 2009;114(15):3139-46 PMID:19638622
- Harousseau JL, Dreyling M. Multiple myeloma: ESMO clinical recommendations for diagnosis, treatment and follow-up. Ann Oncol 2009;20(s4):97-9 PMID:19454476
- Harris JC, Harding SJ, Fourrier N, Drayson MT, Mead GP, Bradwell AR. Nephelometric immunoassays for IgA kappa and IgA lambda quantification for the assessment of patients with multiple myeloma. Clin Chem 2009;C49a
- Hata H, Nishi K, Oshihara W, Arai J, Shimizu K, Kawakita T et al. Adsorption of Bence-Jones protein to polymethylmethacrylate membrane in primary amyloidosis. Amyloid 2009;16(2):108-10 PMID:20536405
- Haynes R, Hutchison CA, Dasgupta T, Emberson J, Wheeler DC, Townend J et al. Associations of serum free light chains (FLCs) with the risks of end-stage renal disease (ESRD) and of death in chronic kidney disease. Presented at ASN Renal Week 2009;TH-PO552a
- Heher EC, Spitzer TR, Goes NB. Light chains: heavy burden in kidney transplantation. Transplantation 2009;87(7):947-52 PMID:19352111
- Herrera GA. Renal lesions associated with plasma cell dyscrasias: practical approach to diagnosis, new concepts, and challenges. Arch Pathol Lab Med 2009;133(2):249-67 PMID:19195968
- Higgins C. Myeloma and monoclonal gammopathy of undetermined significance. Biomed Sci 2009;September
- Hobbs J, Legg A, Giroux M. Clinical applications of serum free light chain analysis. Biomed Sci 2009;April:285-6
- Hobbs JA, Drayson MT, Sharp K, Harding S, Bradwell AR, Mead GP. Frequency of altered monoclonal protein production at relapse of multiple myeloma. Br J Haematol 2009;148(4):659-61 PMID:19863537
- Hobbs JA, Sharp K, Harding S, Drayson M, Bradwell AR, Mead GP. Changes in M-protein at multiple myeloma relapse. Clin Lymphoma Myeloma 2009;9(s1):A162a
- Holding S. Serum free light chain used with electrophoresis increases sensitivity for monoclonal gammopathies. Clin Lymphoma Myeloma 2009;9(s1):A189a
- Hughes M, Soutar R, Lucraft H, Owen R, Bird J. Guidelines on the diagnosis and management of solitary plasmacytoma of bone, extramedullary plasmacytoma and multiple solitary plasmacytomas: 2009 update. Online publication 2009.http://www.bcshguidelines.com/documents/solitary_plamacytoma_bcsh_FINAL_190109.pdf
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- Snyder M, Dispenzieri A, Rajkumar SV, Kyle R, Benson J, Katzmann JA. The biologic and analytic variability of serum protein electrophoresis M-spike, nephelometric Ig quantitation, serum FLC quantitation, and urine M-spike in monoclonal gammopathies. Blood 2009;114(22):1803a
- Stewart AK, Richardson PG, San-Miguel JF. How I treat multiple myeloma in younger patients. Blood 2009;114(27):5436-43
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- Telio D, Bailey D, Chen C, Crump M, Reece DE, Kukreti V. Two distinct syndromes of lymphoma-associated amyloidosis: findings from a case series. Blood 2009;114(22):2938a
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- Tuck HH, James GW. Spontaneous tumor lysis syndrome caused by high grade plasma cell dyscrasia. Presented at ASN Renal Week 2009;PUB652a
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- Van Hoeven K, Wells J, Abadie J. Serum protein electrophoresis (SPEP) plus serum free light chain (sFLC) testing: a sensitive panel for diagnosis of monoclonal gammopathy (MG). Presented at NKF Spring Clinical Meeting 2009
- van Hoeven KH, Bilotti E, McBride L, Berges T, McNeill A, Schillen D, Siegel D. Serum free light chain assays are more sensitive than urinary tests for light chain monoclonal proteins. Clin Chem 2009;55(s6):C30a
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- Weiss BM, Abadie J, Verma P, Howard RS, Kuehl WM. A monoclonal gammopathy precedes multiple myeloma in most patients. Blood 2009;113(22):5418-22 PMID:19234139
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- Willenbacher E, Nachbaur D, Gastl G, Gasser S. Free light chain (by rFLC) monitoring reveals early relapse after HSCT. Clin Lymphoma Myeloma 2009;9(s1):A326a
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2010
- Abdalla S. Serum free light chain (sFLC) assays in patients with unquantifiable low-level parprotein (LLPP) and transient paraproteinaemia (TP). Hematology Reports 2010;2(s2):C35a
- Adballa S. Serum free light chain assays (sFLC) in patients with MGUS attending the Haematology Department at St. Mary's Hospital in London. Hematology Reports 2010;2(s2):B16a
- Ahmed H, Simpson S, Roy A. Normal serum free light chain ratio at presentation is more common in IgA-κ multiple myeloma: a single centre observational study. Hematology Reports 2010;2(s2):B17a
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- Assi LK, Hughes RG, Gunson B, Webb G, Adams DH. Polyclonally raised serum free light chains in liver disease compared to markers of liver damage. Hematology Reports 2010;2(s2):E49a
- Assi LK, Hughes RG, Gunson B, Webb GM, Drayson MT, Bradwell AR, Adams DH. Abnormally elevated serum free light chains in patients with liver disease. Presented at EASL Conference 2010
- Ayliffe N, Sumar N, Behrens J. Bone marrow cell populations and serum free light chain levels in monoclonal gammopathy patients. Hematology Reports 2010;2(s2):A11a
- Azais I, Brault R, Debiais F. New treatments for myeloma. Joint Bone Spine 2010;77(1):20-6 PMID:20031467
- Bae SY, Lee JJ. Multiple myeloma with huge extramedullary plasmacytomas. Korean J Hematol 2010;45(2):88 PMID:1120184
- Barbosa-de-Carvalho NM, Morais-Sarmento-Campos ML. Identificacion de cadenas ligeras libres en suero y su aplicacíon en las gammapatias monoclonales. Hematología 2010;11(4):199-207
- Basnayake K, Ying WZ, Wang PX, Cockwell P, Bradwell A, Hutchison C, Sanders PW. Myeloma light chains activate tubular epithelial cells by a c-Src mediated redox signaling mechanism. Presented at BRS/RA Conference 2010;P238a
- Basnayake K, Ying WZ, Wang PX, Sanders PW. Immunoglobulin light chains activate tubular epithelial cells through redox signaling. J Am Soc Nephrol 2010;21(7):1165-73 PMID:20558542
- Basnayake K, Cheung CK, Sheaff M, Fuggle W, Kamel D, Nakoinz S et al. Differential progression of renal scarring and determinants of late renal recovery in sustained dialysis dependent acute kidney injury secondary to myeloma kidney. J Clin Pathol 2010;63(10):884-7 PMID:20876319
- Basnayake K, Ghonimi T, Sanders P, Hutchison C, Stringer S, Bradwell A, Cockwell P. An assessment of the pathogenicity of polyclonal free light chains in chronic kidney disease. Presented at BRS/RA Conference 2010;P240a
- Basnayake K, Cheung CK, Hutchison C, Stringer S, Cook M, Rylance P et al. Differential progression of renal scarring and determinants of late renal recovery in sustained dialysis dependent acute kidney injury secondary to myeloma kidney. Presented at BRS/RA Conference 2010;P239a
- Bazari H, Attar EC, Dahl DM, Uppot RN, Colvin RB. Case records of the Massachusetts General Hospital. Case 23-2010. A 49-year-old man with erythrocytosis, perinephric fluid collections, and renal failure. N Engl J Med 2010;363(5):463-75 PMID:20818867
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