Resource-stratified guidelines from the Asian Myeloma Network were initially published in 2013  and subsequently updated in 2018 . These recommendations take into consideration differing health care resources across Asian countries.
When limited resources are available, the recommended diagnostic tests to establish a diagnosis of MM include serum and urine electrophoresis and sFLC analysis. This testing algorithm is also recommended for resource-abundant facilities.
In resource-constrained facilities, it is recommended that response to treatment is defined according to IMWG uniform response criteria, which includes sFLC analysis (Section 25.3.5), but routine evaluation of MRD is not required. This is because access to novel agents and SCT is still not universal, and a conventional CR remains a desirable treatment goal that is attained by only a minority of patients.
In resource-abundant healthcare systems, response evaluation can include MRD assessment, which is based on PET-CT imaging and NGF and NGS tests.